Тага, Katherine and Fenton have been best friends since they were teenagers. Now in their early thirties, they've been living it up in London for ten years. But what have they got to show for it? Sure, Tara's got her boyfriend - but she loves food, shopping and her lipstick so much more. Katherine, on the other hand, is a serial singleton whose neatness fetish won't let a man mess up her life. And Fenton? Well, Fenton has everything. Until he gets ill and he has to ask himself: what have you got if you haven't got your health? All three are drinking in the Last Chance Saloon and they're about to discover that if you don't change your life, life has a way of changing you ...